L-Alpha glycerylphosphorylcholine, better known as alpha-GPC, is a natural choline compound found in the brain. Only recently acknowledged as a nutrient by the Institute of Medicine in 1998, alpha-GPC has been the center of attention in numerous studies for its effects in cell messaging, nervous system development, DNA synthesis, and more. Many Americans do not get the recommended amounts of choline in their diet, and postmenopausal women are especially vulnerable to choline definiciency.